Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis
It has been suggested that cancer stem cells (CSC) may play a central role in oncogenesis, especially in undifferentiated tumours.Anaplastic thyroid carcinoma (ATC) has characteristics suggestive of a tumour enriched in CSC.Previous studies suggested that the stem cell factor SOX2 has a preeminent hierarchical role in determining the characteristic